Shereen Farag, Departamento de Cardiología, Facultad de Medicina, Benha University, Benha, Egipto
Shaimaa Mostafa, Departamento de Cardiología, Facultad de Medicina, Benha University, Benha, Egipto
Khaled El-Rabbat, Departamento de Cardiología, Facultad de Medicina, Benha University, Benha, Egipto
Ahmed Abd El-Aziz, Departamento de Cardiología, Facultad de Medicina, Benha University, Benha, Egipto
Introduction: Acute coronary syndrome (ACS) and its complication are one of the major health problems worldwide. Numerous clinical risk scores have been used to stratify ACS patients. Objective: to evaluate the relationship between risk scores (TIMI, PURSUIT, and GRACE) and short-term outcomes in acute coronary syndrome (ACS) patients. Method: the study enrolled 500 patients with ACS. Risk scores were evaluated at admission and correlated with outcomes during in-hospital admission and three months following discharge. Results: the study included 500 patients with ACS, mean age was 57.4 ± 11.8 years. The mean TIMI, GRACE, and PURSUIT score was 2.7 ± 1.9, 138.8 ± 39.6, and 10.9 ± 4.9, respectively. Higher TIMI, GRACE, and PURSUIT scores were associated with higher in-hospital and short-term morbidity and mortality. PURSUIT score was the most significant predictor among the three scores for the incidence of in-hospital heart failure using a cut-off value > 15.5 with a sensitivity of 82.2% and specificity of 96.9%. At the same time, the GRACE score was the most accurate predictor of recurrent ischemia and heart failure during three months of follow-up, using cut-off values > 117.5 and > 118.5, with a sensitivity 100%, 100% and specificity of 64%, 62.2%, respectively. Conclusion: risk scores are straightforward, bedside-applicable, and capable of predicting adverse outcomes during hospitalization and three months after.
Keywords: Acute coronary syndrome. TIMI score. GRACE score. PURSUIT score.
