Ledmar J. Vargas-Rodríguez, Departamento de Medicina Interna, Hospital San Rafael, Tunja; Facultad de Ciencias de la Salud, Universidad de Boyacá, Programa de Medicina, Tunja; Colombia
Elkin D. Bedoya-Pérez, Programa de Medicina, Fundación Universitaria de Ciencias de la Salud, Bogotá, Colombia
Edwar J. Rozo-Ortiz, Departamento de Medicina Interna, Hospital San Rafael, Tunja; Facultad de Ciencias de la Salud, Universidad de Boyacá, Programa de Medicina, Tunja; Colombia
Javier O. Barón-Barón, Departamento de Medicina Interna, Hospital San Rafael, Tunja; Facultad de Ciencias de la Salud, Universidad de Boyacá, Programa de Medicina, Tunja; Colombia
Introduction: infective endocarditis (IE) is a multisystem disease resulting from infection, usually bacterial, of the endocardial surface of the heart. Objective: to determine the factors associated with infectious endocarditis in patients treated at the San Rafael University Hospital in Tunja. Materials and method: design: Case-control study. Setting: Hospital. Participants: People with infectious endocarditis who were treated at the San Rafael Hospital in Tunja between 2009 and 2019. Variables: The dependent variable was the presence of infectious endocarditis diagnosed using the Duke criteria. Independent variables were included that corresponded to sociodemographic, clinical and background information of the participants. Results: 87 cases and 175 controls were included, where it was found that the variables chronic kidney disease (OR: 145), dental implants (OR: 77), autoimmune disease (OR: 61), male sex (OR: 15), urinary tract infection in the last month (OR: 15), arrhythmias (OR: 13), valvulopathies (OR: 6), pharyngotonsillitis (OR 5) and use of proton pump inhibitors (OR 2) are risk factors, while the use of aspirin (OR: 0.029) decreases the probability of presenting endocarditis. Conclusions: the factors associated with endocarditis in the emergency department of the San Rafael University Hospital in Tunja between 2009 and 2019 are, in order of importance: Chronic kidney disease, dental implants, autoimmune disease, male sex, urinary tract infection in the last month, arrhythmias, valvular disease, pharyngotonsillitis, and use of proton pump inhibitors (PPIs), while aspirin use is a protective factor.
Keywords: Endocarditis. Infection. Risk factors. Bacteriemia.
