Echocardiographic measurements of the left ventricle in heart failure with and without a history of heart transplant: exploratory analysis




Alberto Guevara-Tirado, Facultad de Medicina, Universidad Científica del Sur. Lima, Perú


Introduction: Class B heart failure or higher generates changes in the walls of the left ventricle, which can be more severe in patients with a history of heart transplant. Objective: To analyze the echocardiographic differences of the left ventricular walls in patients with heart failure with and without a history of heart transplant. Methods: Analytical and cross-sectional study of 24,689 patients with class B heart failure or higher. The decision tree was used by automatic detection of chi-square interactions. Results: Patients with heart failure and a history of heart transplantation had greater echocardiographic measurements and left ventricular dilation 1.66 times more frequently than those without a history (PR = 1.66; 95% CI = 1.163-2.388). The classification tree for heart failure with and without transplant for men had the characteristics associated with left ventricular change: thickness of the interventricular septum and end-diastolic ventricular internal diameter. In women, it includes: posterior wall distance and thickness of the end-diastolic interventricular septum. Conclusions: Echocardiographic measurements and frequency of left ventricular dilation were higher in heart failure and a history of heart transplant. Echocardiographic measurements and characteristics in this patient population differ by sex.



Keywords: Heart failure. Heart transplantation. Echocardiography. Ventricular dysfunction left. Supervised machine learning.